'Switch-off' biosensing for chymotrypsin-catalyzed reaction by SPR-SERS spectroscopy.
نویسندگان
چکیده
We describe a novel 'switch-off' biosensing strategy for the detection of chymotrypsin based on surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) spectroscopy. This approach analyzes the fingerprint spectrum of the chymotrypsin-catalyzed substrate. The lowest probed concentration is 0.4 nM for chymotrypsin.
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عنوان ژورنال:
- The Analyst
دوره 138 21 شماره
صفحات -
تاریخ انتشار 2013